The scandal of regenerative medicine surgeon Paolo Macchiarini and his deadly plastic tracheas made world news. Yet this human abuse, which started at the Karolinska Institutet in Sweden, was just a part of a much bigger horror story. The suffering and deaths of other trachea transplant patients of Macchiarini and his collaborators, those who received a decellurised cadaveric trachea, is much less known. I focused my reporting on it, bringing back to memory all those dead patients which the hospitals in London, Florence and Barcelona pretend never existed. Presently, 62 patients were scheduled to be treated with decellurised cadaveric trachea in two phase 1 clinical trials in UK and one EU-funded phase 2 clinical trial, all led by former Macchiarini partner, UCL laryngologist Martin Birchall. But now, all 3 clinical trials are not going anywhere. Read more [...]
Changing the environment in which scientists evolve requires considerable cultural changes. In this exclusive interview, EuroScientist talks to Hans Wigzell, one of the most influential scientists in Europe and former president of the Karolinska Institute, Stockholm, Sweden. Although he recognises the necessity of bureaucrats in research institutions, he denounces their intervention as micromanagers of research. He also shares his views on what is required to, literally, let scientists free from bureaucrats. The solution he advocates involves strong leadership in research to remove the need for bureaucratic rules. Read more [...]
A star scientist overstating the outcome of his pioneering transplant experiments may be worrying. But when these experiments are performed in humans, used a guinea pigs, before laboratory research proves the validity of the approach, we have a recipe for disaster. The recent Macchiarini scandal has led to one of the most shocking case of scientific misconduct in recent years. It reveals a lot about the vanity culture pervading some fields of research. Our outlook on what constitutes success in research may need to be revised. Read more [...]
European science conversations by the community, for the community
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