History reveals a succession of many dawns and twilights, in different facets of human activity. Looking at the past, we can date and understand the reasons for the birth of science, specifically fundamental science. However, we do not know precisely when its twilight will take place. Nevertheless, clues of the advent of such twilight are already in the air. This article presents the underlying rationale suggesting that we are now past the golden age of pure science, and how we need to accommodate our research to this new era. Read more [...]