Public databases of the toxic effects of chemicals that have been registered under the REACH directive have been sitting idle for too long. In an opinion piece, Thomas Hartung explains how the development of software by his team at the Bloomberg School of Public Health, at Johns Hopkins University, USA, helps make sense of the large volume of chemical database content. Now that they made such data machine readable, expectations are that it will soon be possible to provide open access to such public database. Ultimately, this could substantially decrease the number of animal tests. Indeed, the database makes it possible to do so-called read-across, allowing to infer toxicity of heaps of untested chemicals from existing data on chemicals of similar structure, which have already been tested. Read more [...]