This article reviews the Nobel history since inception which shows that the Prizes in science conferred on individuals in the first 50 years are shifting to the Prizes being shared. It is,in part, because the science has become more complex, collaborative, expansive, and expensive. With the critical need for teamwork to tackle Big Science, we recommend that the policy of “no more than three” sharing the Prize be loosened on case by case basis and the nomination be made open for scientific organisations. We also suggest concrete steps for improving the gender gap among the Nobel Laureates. This necessitates proactive nominations of Nobel worthy work done by women and making structural changes in Nobel committees toward better gender ratio. Finally, our analysis shows that the U.S. is emerging as a Nobel Super Power leading to a divide not only with European countries but the world at large.